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About Joshua Mali, MD, FASRS
Board-certified retina specialist and vitreoretinal surgeon, Fellow of the American Society of Retina Specialists, and Founder and CEO of Mali Enterprises. Here is the full record: clinical expertise, honors, editorial and leadership roles, publications and service.
Retina clinical trial experience
A clinical trial expert, Dr. Mali has served as principal investigator for global sponsors across the most active areas of retina drug development.
- AllerganPrincipal investigator
SEQUOIA
Safety and efficacy of abicipar pegol in neovascular age-related macular degeneration.
- RegeneronPrincipal investigator
PANORAMA
Intravitreal aflibercept for moderately severe to severe nonproliferative diabetic retinopathy.
- SantenPrincipal investigator
DE-109
Intravitreal sirolimus (440 µg) for active, non-infectious uveitis of the posterior segment.
- Chengdu KanghongPrincipal investigator
KHB-1801
Multicenter, dose-ranging study of conbercept in neovascular age-related macular degeneration.
- OptheaPrincipal investigator
OPT-302-1004
OPT-302 in combination with ranibizumab versus ranibizumab alone in neovascular AMD.
Clinical expertise
Board-certified in ophthalmology and fellowship-trained in medical and surgical vitreoretinal disease, Dr. Mali uses advanced surgical techniques and technology to care for patients with complex retinal conditions.
Macular degeneration
Neovascular AMD, geographic atrophy and next-generation therapies.
Diabetic eye disease
Diabetic retinopathy and macular edema, including sustained-release steroid implants.
Uveitis
Non-infectious posterior uveitis and emerging treatments.
Retinal vascular disease
Retinal vein and artery occlusions.
Vitreoretinal surgery
Retinal detachment, trauma, intraocular foreign bodies and complex surgical cases.
Innovation in retina
Artificial intelligence, biosimilars, drug delivery and home monitoring.
In the field





“Miracle maker. When you look in someone’s eyes and see the perfection you accomplish, providing an excellent outcome.”
Stitched into a needlepoint by a patient after her surgeries with Dr. Mali, so happy she could see again and return to her artwork.
Awards and recognition

- 2026 and 2025
Castle Connolly Top Doctor
- 2025
Distinguished Alumnus, Eberly College of Arts and Sciences
West Virginia University
- 2023
Healio Honors
Recognizing healthcare professionals who go above and beyond for their patients and their field.
- 2023
Champions of Healthcare Award Finalist
- 2022
American Academy of Ophthalmology LEO Award
- 2022
Gold Quill Award
- 2022
Winning Pitch Challenge, Honorable Mention
For the SNAPS Eyeshield, ASCRS Annual Meeting, Washington, DC.
- 2021
Fellow of the American Society of Retina Specialists
- 2020
America’s Top Ophthalmologist
- 2019
AAO Global ONE Network Surgical Video Award
Following the ONE Network Editor’s Choice Award in 2018.
- 2019
West Virginia University Homecoming Parade Marshal
- 2018
Winning Pitch Challenge, Honorable Mention
For the Mali Eyeglass Holder, ASRS Annual Meeting, Vancouver.
- 2018
Outstanding Alumnus, WVU Department of Biology
- 2018
Marquis Who’s Who in America Lifetime Achievement Award
- 2015
ASRS Innovative Retina Surgical Video Series
Featured video, and winner of the Vit-Buckle Society travel grant video contest.
Leadership roles
- Mali EnterprisesFounder and Chief Executive Officer, since 2018
- American Board of OphthalmologyOral board examiner; 2024 Content Outline Committee
- Macular Degeneration AssociationMedical Director, 2018–2022
- Retina Summit 2022Program Chair
Editorial roles
- Ocular Surgery NewsEditorial advisory board, since 2020
- Modern RetinaEditorial advisory board, since 2020
- Ophthalmology TimesRegular contributing author, since 2015
- HCPLiveEditorial advisory board, since 2020
- Ophthalmology 360Editorial advisory board, since 2021
- Healio and Ocular Surgery NewsRegular contributing author, since 2018
Selected publications and presentations
Endogenous endophthalmitis with iris abscess after routine dental cleaning
JAMA Ophthalmology, 2015Changing the game in treatment of acute pseudophakic CME
Ophthalmology Times, 2017Surgeon designs, patents tabletop eyeglass holder
Primary Care Optometry News (Healio), 2019Effectiveness of 190 µg fluocinolone acetonide and 700 µg dexamethasone intravitreal implants in diabetic macular edema using the area-under-the-curve method: the CONSTANT analysis
Clinical Ophthalmology, 2020; ASRS Annual Meeting, Chicago, 2019SNAPS Eye Shield: creating the gold standard for postoperative ocular protection
Modern Retina, 2023Treatment of refractory acute retinal necrosis with intravenous foscarnet or cidofovir
Ocular Immunology and Inflammation, 2016Removal of a large metallic intraocular foreign body
AAO ONE Network, Editor’s Choice and Global ONE Network awardsChoosing the optimal corticosteroid for DME prior to the fluocinolone acetonide implant
ASRS Annual Meeting, Vancouver, 2018Micro-Sized Wonders: ILUVIEN
Image of the Month, The Ophthalmologist, 2018Effect of agalsidase beta on corneal verticillata in Fabry disease
AAO Annual Meeting, 2015; Journal of Clinical & Experimental Ophthalmology, 2016Metallic intraocular foreign body removal
ASRS Innovative Retina Surgical Video SeriesFluocinolone acetonide intravitreal implant in vitreous
ASRS Retina Image BankDifferent fellowship structures
Retina Today, 2015Patient exhibits corneal verticillata for more than 20 years
Primary Care Optometry News (Healio)Argon laser punctal stenosis in contact lens–induced dry eye
Eye & Contact Lens, 2010
Service to others
Dr. Mali has performed cataract surgery as a volunteer surgeon for Medical Ministry International in southern Mexico, and traveled with the Bahá’í-inspired Health for Humanity to deliver medical supplies and care to a hospital serving an impoverished area of Managua, Nicaragua. He has served as a volunteer ophthalmologist with Remote Area Medical, volunteered with the Georgia Lions Camp for the Blind and Camp Abilities with the Columbia Lighthouse for the Blind, and mentored a NASA and FIRST-sponsored robotics team.
Work with Dr. Mali
For advisory work, due diligence, media or speaking, get in touch.
Contact Dr. Mali